采用铁离子还原/抗氧化力测定法(ferric reducing/antioxidant power assay,FRAP)、邻苯三酚法、水杨酸法,比较研究桑黄不同极性组分的抗氧化活性。结果显示,4种桑黄不同组分体外总抗氧化能力高低顺序依次是:水溶性组分>乙酸乙酯组分>乙醇组分。在清除羟自由基(·OH)试验中发现石油醚组分对羟自由基清除能力最强,远远高于水溶性成分,乙酸乙酯组分和乙醇组分也很强。在清除超氧阴离子(O^(2-)·)试验中发现乙醇组分活性最高,石油醚组分次之。
从甘肃天祝县的蝎子七全草中分离鉴定出了15个化合物,其中2个为新化合物.报道9个已知化合物:阿魏酸、4 豆甾烯 3 酮、紫丁香甙、5,8,2′ 三羟基 5′ 甲氧基双氢黄酮、异鼠李素、槲皮素 3 O 鼠李素、山奈素 3 O β D 葡萄糖甙、洋芥素 7 O β D 葡萄糖甙、5 羟基 4 甲氧基黄酮 7 O β 芸香甙.上述成分均首次从该植物中分离.
A simple, sensible and reliable HPLC-DAD fingerprint analysis method for the raw materials of Oxytropisfalcata and Oxytropis chiliophylla, both of which were used as ＂Er-Da-Xia＂ in Tibetan medicines, was developed and then subsequently applied to analyze samples collected from different locations or times. 19 common fingerprint peaks for O. falcata, 24 for O. chiliophylla, and 11 for the two herbs were designated respectively, including 7 identified characteristic peaks existing in both herbs and 1 uniquely presenting in O. chiliophylla. Although there were some slight differences in the chemicals of O. falcata and O. chiliophylla, the main components of both herbs were consistent generally. The results provided scientific basis, at least from the chemical point of view, for the reasonablity of two herbs being used as the same drug in Tibetan medicines and for the necessary of further investigation on their detailed chemical and pharmacological differences.
