In the present paper the design of oligopeptides and pseudopeptides treating thr ombosis and osteoporosis, such as peptide 6A and its analogs, hybrid peptides of peptide 6A or its analogs and RGD peptides, cyclic peptide 6A or its analogs, n itronyl nitroxide containing peptide 6A or its analogs and RGD peptides, estroge n-GHRPs, hydrocortisone-Kyotophin, hydrocortisone-urotoxins, prednisolone-ur otoxins, and estrogen-RGD peptides, was reviewed.