开心散,始载于唐代孙思邈所著的《备急千金要方》,由石菖蒲、远志、人参、茯苓4味中药配伍而成,具有益气养心、安神定志的功效。本文通过查阅文献资料对开心散的处方进行考证,并探讨其在现代临床中的应用,以期为开心散的现代化应用提供了理论基础和实践指导。Kaixin Powder, first recorded in the “Beiji Qianjin Yaofang: Essential Prescriptions for Emergencies Worth a Thousand Gold Pieces” compiled by Sun Simiao of the Tang Dynasty, is a traditional Chinese medicine formula consisting of four herbs: Acorus tatarinowii, Polygala tenuifolia, Panax ginseng, and Poria cocos. It is known for its efficacy in nourishing qi and the heart, calming the nerves, and stabilizing the mind. This article conducts textual research on the prescription of Kaixin Powder by consulting literature and discusses its application in modern clinical practice, aiming to provide a theoretical foundation and practical guidance for the modern application of Kaixin Powder.