Objective:To investigate mental health state of primary-middle school teachers in Guangdong.Methods:1321 primary-middle school teachers in Guangdong were administered SCL-90. Results:The mental health of Primary-middle school teachers was worse than that of Chinese norm, and 23.92% of them was worse in at least one item. There was significant difference between different teacher groups. The mental health of teachers from primary school,especially the male teachers and teaders with lower educational level was an important issue.Conclusion: Primary-middle school teachers need more help to improve their mental health.