A low-power voltage-mode-logic (VML) transmitter fabricated in TSMC 28 nm CMOS technology is presented. The VML driver outputs a high-swing signal and consumes less power than a current-mode-logic (CML) driver. To further reduce power, the driver is divided into two voltage domains by level shifters. Moreover, the proposed driver topology can achieve mutually decoupled impedance self-calibration and equalization control. The measurement result shows that the transmitter merely dissipates 23 roW/channel while exhibiting an 880 mV differential eye height at 4.488 Gb/s.