The positive partial transposition(PPT)criterion and the realignment criterion constitute two of the most important criteria for detecting entanglement.The generalized partial transposition(GPT)criterion which contains the PPT criterion and the realignment criterion as special cases,provides a necessary condition for a multipartite state to be separable.Here we extend the GPT criterion to the infinitedimensional multipartite(bipartite)case and show that it includes multipartite(bipartite)PPT criterion and multipartite(bipartite)realignment criterion as special cases as well.