Five novel donor-acceptor （D-A） conjugated cooligomers （F4B-hP, F5B-hP, F5B2[1,2]-hP, F5B2[I,3]-hP and F7B2[1,2]-hP） were synthesized. The absorption spectra of the cooligomers cover a wide range from 300 nm to 630 nm. The cooligomers could form films featured by alternating D-A lamellar nanostructures with the periods relative to the molecular lengths after thermal annealing or solvent vapor annealing. Single molecule solar cells were fabricated, and FSB-hP exhibited the best device performance. When the film of FSB-hP was thermally annealed, a power conversion efficiency （PCE） of 1.56% was realized. With solvent vapor annealing, the PCE could be further improved to 1.72% with a short-circuit current （J_SC） of 5.76 mA/cm2, an open-circuit voltage （Voc） of 0.87 V and a fill factor （FF） of 0.34.
