＜正＞In recent years,xanthenes especially benzoxanthens have attracted attention of chemists due to their wide r...
Jianan Jin~1,Jianmin Zhang~(1,2*),Wenli Shang~1,Subo Shen~1,Cong Liu~1, Shizheng Zhu~(2*) 1 Department of Chemistry,School of Science,Shanghai University,No.99,Shangda Road, Shanghai 200444,China 2 Key Laboratory of Organofluorine Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,354 Fenglin Lu,Shanghai 200032,China.
In the presence of Cu（I） and triethyl amine, one-pot three-component reaction of fluoroalkanesulfonyl azides, alkynes and iminophosphoranes in CH2Cl2 at room temperature gave a novel class of fluorinated phosphorus amidines in good yields.
A novel and facile preparation of l,l-difluoroallyl substituted five-membered lactones or pyrrolidines in mod- erate yields through direct double electrophilic fluorination of 4,5-allenoic acids or tosylamides with SelectfluorTM F-TEAD-BF4 is described.
We have developed an efficient method to achieve N-gem-difluorocyclopropylation of N-heterocycles with the use of gem-difluorocyclopropyl tosylate as a building block under mild conditions, gem- Difluorocyclopropyl tosylates could be easily prepared on a large scale and exhibit great stability.
Enantioselective synthesis of functionalized fluorinated dihydropyrano[2,3-c]pyrazoles has been achieved via a diaminocyclohexane-thiourea catalyzed cascade Michael addition and Thorpe-Ziegler type cyclization in high yields （up to 98%） with moderate to good enantioselectivity （up to 90% ee）.
The copper-mediated trifluoromethylation of terminal alkynes with S-（trifluoromethyl）diarylsulfonium salt has been carefully investigated. The reactions proceeded smoothly to afford trifluoromethylated acetylenes in moderate to good yields. This approach is a convenient method to synthesize a variety of functional trifluoromethylated acetylenes.
