An investigation on the dynamic response of a top tensioned riser (TTR) under combined excitation of internal solitary wave, surface wave and vessel motion is presented in this paper. The riser is idealized as a tensioned slender beam with dynamic boundary conditions. The KdV-mKdV equation is chosen to simulate the internal solitary wave, and the vessel motion is analysed by using the method proposed by Sexton. Using finite element method, the governing equation is solved in time domain with Newmark-13 method. The computation programs for solving the differential equations in time domain are compiled and numerical results are obtained, including dimensionless displacement and stress. The action of internal solitary wave on the riser is like a slow powerful impact, and is much larger than those of surface wave and vessel motion. When the riser is under combined excitation, it vibrates at frequencies of both surface wave and vessel motion, and the vibration is dominated by internal solitary wave. As the internal solitary wave crest passes by the centre of the riser, the maximum displacement and stress along the riser occur. Compared to the lower part, the displacement and stress of the riser in the upper part are much larger.