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国家自然科学基金(20676041)

作品数:3 被引量:1H指数:1
相关作者:姜建国陈倩更多>>
相关机构:华南理工大学更多>>
发文基金:国家自然科学基金中国博士后科学基金更多>>
相关领域:化学工程生物学更多>>

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蓝藻门中类胡萝卜素合成关键酶基因的水平转移分析
2007年
类胡萝卜素合成酶基因(crt基因)是一类指导类胡萝卜素合成的基因,迄今为止还没有人很好地阐述蓝藻crt基因序列的多样性和早期进化特征.为研究蓝藻crt基因的多样化程度,了解其进化规律,文中利用现有资料,分析了参与蓝藻门中类胡萝卜素代谢的关键酶的分子进化关系,主要目的是提供crt基因在蓝藻门中的进化轮廓,分析其是否存在基因的水平转移,并评价其选择方式,便于今后描述该基因在蓝藻中的进化特征.系统发育分析发现在蓝藻基因组中频繁发生基因的水平转移,而氨基酸变化大部分是在正向选择下进化的.分析还发现大部分代谢前期的crt基因相对保守,一些亲缘关系密切的蓝藻其类胡萝卜素基因却有较远的进化距离.
陈倩姜建国
关键词:蓝藻系统发育分子进化基因水平转移
Chemical composition and larvicidal effects of essential oil of Blumea martiniana against Anopheles anthropophagus被引量:1
2011年
Objective:To determine chemical composition of the hydrodistilled essential oil of Blumea martiniana,and to evaluate its larvicidal activity against Anopheles anthropophagus,the natural vector of malaria.Methods:Chemical composition of essential oils extracted by steam distillation was investigated by gas chromatography and mass spectroscopy(GC-MS).Larvicidal activity of essential oil and its four main compounds was carried out by WHO method.Twenty larvae of early fourth-instar stage were used in the larvicidal assay and five replicates were maintained for each concentration.The 24 h LC50 and LC90 values were determined following probit analysis.Results:Totally 68 compounds corresponding to 98.55%of the total oil were identified and the major constituents of essential oil were:linalool(10.36%),germacrene D(9.09%), borneol(6.24%),γ-terpinene(5.38%).The oil and linalool,germacrene D,bomeol,γ-terpinene exerted significant larvicidal activity with LC50 values of 46.86,35.87,44.61,35.89,and 29.21 mg/L, respectively.It also showed a dose dependent effect on mortality.Conclusions:The essential oil of Blumea martiniana and its four major compounds may have potential for use in control of Anopheles anthropophagus larvae and could be useful in search of newer,safer and more effective natural compounds as larvicides.
Liang ZhuYing-juan Tian
关键词:ESSENTIALOILCOMPOSITIONLARVICIDALANOPHELES
A new flavone glycoside from Cancrinia discoidea(Ledeb.) Poljak
2010年
A new flavone glucoside,selagin-7-O-(6″-O-acetyl-)-β-D-glycoside,has been isolated from Cancrinia discoidea(Ledeb.) Poljak.Its structure was identified by spectroscopic methods,2D NMR and MS.Compounds exhibited activity of anti-inflammatory in vitro.
Liang Zhu Ying Juan Tian
关键词:ANTI-INFLAMMATORY
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