This paper deals with a multi-objective parameter optimization framework for energy saving in injection molding process.It combines an experimental design by Taguchi's method,a process analysis by analysis of variance(ANOVA),a process modeling algorithm by artificial neural network(ANN),and a multi-objective parameter optimization algorithm by genetic algorithm(GA)-based lexicographic method.Local and global Pareto analyses show the trade-off between product quality and energy consumption.The implementation of the proposed framework can reduce the energy consumption significantly in laboratory scale tests,and at the same time,the product quality can meet the pre-determined requirements.