Synthesis and ring-opening reaction of TADDOL analogue with cyclopropane as chiral backbone were described. A plausible ring-opening and carbonium ion rearrangement mechanism have been proposed.
Jun LIU Qing Hua BIAN Ming An WANG Hong Chao GUO Min WANG
Three novel chiral selectors 4a-c were synthesized from （S）-amino acids and （R）-1-phenyl-2-（4-methylphenyl）ethylamine. 4a-c were connected to 3-aminopropylsilanized silica gel to be used as the chiral stationary phase for HPLC. Five amino acid derivatives and two pyrethroid insecticides were fairly resolved on these three new chiral stationary phases under normal phase condition.
