An SIS model with periodic maximum infectious force, recruitment rate and the removal rate of the infectives has been investigated in this article. Sufficient conditions for the permanence and extinction of the disease are obtained. Furthermore, the existence and global stability of positive periodic solution are established. Finally, we present a procedure by which one can control the parameters of the model to keep the infectives stay eventually in a desired set.
The SEIR epidemic model studied here includes constant inflows of new susceptibles, exposeds, infectives, and recovereds. This model also incorporates a population size dependent contact rate and a disease-related death. As the infected fraction cannot be eliminated from the population, this kind of model has only the unique endemic equilibrium that is globally asymptotically stable. Under the special case where the new members of immigration are all susceptible, the model considered here shows a threshold phenomenon and a sharp threshold has been obtained. In order to prove the global asymptotical stability of the endemic equilibrium, the authors introduce the change of variable, which can reduce our four-dimensional system to a three-dimensional asymptotical autonomous system with limit equation.