传统检测房室平面位移的方法因测量信息不完整及房室平面特征点跟踪不准等缺点,造成房室平面位移(Atrioventricular Plane Displacement,AVPD)曲线失真。利用图像处理技术结合心血管核磁共振图像(Cardiovascular Magnetic Resonance,CMR)可以更准确地检测室平面位移。首先,采用具有通道和空间可靠性的判别相关滤波器(Discriminative Correlation Filter with Channel and Spatial Reliability,CSR-DCF)增强对房室平面特征点的跟踪能力。其次,基于心脏核磁共振图像的空间信息构建三维的房室平面多面体,从整体上评估房室平面位移。最后,通过主成分分析法(Principal Component Analysis,PCA)重建房室平面的位移曲线。实验表明,本文方法重建后的房室平面位移保留了原始数据信息的96%以上并且房室平面位移曲线更加平滑的同时符合生理特性。
Aims: To examine how left atrioventricular plane displacement(AVPD), a widely used measure of left ventricular(LV) function, is related to presence and degree of aortic stenosis. Methods and results: Cardiac dimensions, LV filling, left A VPD, LV ejection fraction (LVEF), and valve function were assessed by echocardio graphy/Doppler in 182 patients with various cardiac diseases (mean (SD) age 69(1 2) years, 36%women), 49 consecutive with and 133 consecutive without aortic ste nosis. In an analysis of covariance, neither left AVPD nor LVEF was independentl y correlated with the presence of aortic stenosis. However, looking separately a t patients with aortic stenosis, left AVPD (p=0.03) but not LVEF correlated inde pendently with degree of aortic stenosis in multiple linear regression analysis. In patients with aortic stenosis, an abnormal left AVPD had 94%sensitivity and 90%negative predictive value with regard to severe aortic stenosis, compared w ith 56%and 62%, respectively, for LVEF. Conclusion: In patients with cardiac d isease, neither left AVPD nor LVEF correlated independently with presence of aor tic stenosis. However, in patients with aortic stenosis, left AVPD but not LVEF correlated with the degree of aortic valve obstruction and left AVPD but not LVE F had high sensitivity and negative predictive value with regard to severe aorti c stenosis. Compared with LVEF, left AVPD is an earlier and more sensitive marke r of LV haemodynamic load in patients with aortic stenosis.
